Under no circumstances should you use the Incisor. The Mantis that you start out with is a very useful tool, but upgrade to the Viper when you can, and upgrade from the Viper to the Widow when you reach the Collector ship. There are a few Sniper Rifles available in the game, so always try to secure the correct weapon. Powerful and accurate, using it to its fullest purpose is your focus. When I chose an Infiltrator back in Mass Effect, I did so to guide the character as a master of the Sniper Rifle, a focus I have kept in ME2. Mass Effect 2 In Mass Effect 2, I use a strict weapons-based build, focusing around proper use of ammo powers and performance enhancers to deal with each situation.